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1

Education and research are essential for lasting peace in Yemen

Zakham, Fathiah, Vapalahti, Olli, Lashuel, Hilal A

Journal:

Lancet (London, England)

Year:

2020

File:

PDF, 45 KB

2020

2

Characterization of the Transthyretin Acid Denaturation Pathways by Analytical Ultracentrifugation: Implications for Wild-Type, V30M, and L55P Amyloid Fibril Formation †

Lashuel, Hilal A., Lai, Zhihong, Kelly, Jeffery W.

Journal:

Year:

1998

Language:

english

File:

PDF, 242 KB

english, 1998

3

[IEEE 2017 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC) - Munich, Germany (2017.6.25-2017.6.29)] 2017 Conference on Lasers and Electro-Optics Europe & European Quantum Electronics Conference (CLEO/Europe-EQEC) - Mid-infrared plasmonic nanoantennas for protein structure detection

Etezadi, Dordaneh, Warner, John B., Ruggeri, Francesco S., Dietler, Giovanni, Lashuel, Hilal A., Altug, Hatice

Year:

2017

Language:

english

File:

PDF, 261 KB

english, 2017

4

The Role of Intrinsically Unstructured Proteins in Neurodegenerative Diseases

Raychaudhuri, Swasti, Dey, Sucharita, Bhattacharyya, Nitai P., Mukhopadhyay, Debashis, Lashuel, Hilal

Journal:

Year:

2009

Language:

english

File:

PDF, 1.55 MB

english, 2009

5

Chronic corticosterone aggravates behavioural and neuronal symptomatology in a mouse model of alpha-synuclein pathology

Burtscher, Johannes, Copin, Jean-Christophe, Rodrigues, João, Kumar, Senthil T., Chiki, Anass, Guillot de Suduiraut, Marie-Isabelle, Sandi, Carmen, Lashuel, Hilal A.

Journal:

Neurobiology of Aging

Year:

2019

File:

PDF, 17.51 MB

2019

6

A simple, versatile and robust centrifugation‐based filtration protocol for the isolation and quantification of α‐synuclein monomers, oligomers and fibrils: Towards improving experimental reproducibility in α‐synuclein research

Kumar, Senthil T., Donzelli, Sonia, Chiki, Anass, Syed, Muhammed Muazzam Kamil, Lashuel, Hilal A.

Journal:

Journal of Neurochemistry

Year:

2020

Language:

english

File:

PDF, 18.26 MB

english, 2020

7

Phosphorylation of the overlooked tyrosine 310 regulates the structure, aggregation, and microtubule- and lipid-binding properties of Tau

Ait-Bouziad, Nadine, Chiki, Anass, Limorenko, Galina, Xiao, Shifeng, Eliezer, David, Lashuel, Hilal A.

Journal:

Journal of Biological Chemistry

Year:

2020

File:

PDF, 2.66 MB

2020

8

Auflösung von Amyloidaggregaten durch einen kontrolliert induzierten Übergang von einer β-Faltblatt- in eine α-Helix-Struktur: eine Anwendung des Schalterkonzepts

Richard Mimna, Marie-Stéphanie Camus, Adrian Schmid, Gabriele Tuchscherer, Hilal A. Lashuel, Manfred Mutter

Journal:

Angewandte Chemie

Year:

2007

Language:

german

File:

PDF, 386 KB

german, 2007

9

Highly Efficient and Chemoselective Peptide Ubiquitylation

K. S. Ajish Kumar, Mahmood Haj-Yahya, Diana Olschewski, Hilal A. Lashuel, Ashraf Brik

Journal:

Angewandte Chemie

Year:

2009

Language:

english

File:

PDF, 463 KB

english, 2009

10

Wechselwirkungen zwischen amyloidogenen Proteinen und Membranen: Modellsysteme liefern mechanistische Einblicke

Sara M. Butterfield, Hilal A. Lashuel

Journal:

Angewandte Chemie

Year:

2010

Language:

german

File:

PDF, 2.31 MB

german, 2010

11

Towards Elucidation of the Role of Ubiquitination in the Pathogenesis of Parkinson’s Disease with Semisynthetic Ubiquitinated α-Synuclein

Mirva Hejjaoui, Mahmood Haj-Yahya, Dr. K. S. Ajish Kumar, Prof. Ashraf Brik, Prof. Hilal A. Lashuel

Journal:

Angewandte Chemie

Year:

2011

Language:

english

File:

PDF, 642 KB

english, 2011

12

Disruption of Amyloid-Derived Peptide Assemblies through the Controlled Induction of a β-Sheet to α-Helix Transformation: Application of the Switch Concept

Richard Mimna, Marie-Stéphanie Camus, Adrian Schmid, Gabriele Tuchscherer, Hilal A. Lashuel, Manfred Mutter

Journal:

Angewandte Chemie International Edition

Year:

2007

Language:

english

File:

PDF, 386 KB

english, 2007

13

Highly Efficient and Chemoselective Peptide Ubiquitylation

K. S. Ajish Kumar, Mahmood Haj-Yahya, Diana Olschewski, Hilal A. Lashuel, Ashraf Brik

Journal:

Angewandte Chemie International Edition

Year:

2009

Language:

english

File:

PDF, 463 KB

english, 2009

14

Amyloidogenic Protein–Membrane Interactions: Mechanistic Insight from Model Systems

Sara M. Butterfield, Hilal A. Lashuel

Journal:

Angewandte Chemie International Edition

Year:

2010

Language:

english

File:

PDF, 2.50 MB

english, 2010

15

Towards Elucidation of the Role of Ubiquitination in the Pathogenesis of Parkinson’s Disease with Semisynthetic Ubiquitinated α-Synuclein

Mirva Hejjaoui, Mahmood Haj-Yahya, Dr. K. S. Ajish Kumar, Prof. Ashraf Brik, Prof. Hilal A. Lashuel

Journal:

Angewandte Chemie International Edition

Year:

2011

Language:

english

File:

PDF, 631 KB

english, 2011

16

Switch-peptides as folding precursors in self-assembling peptides and amyloid fibrillogenesis

Gabriele Tuchscherer, Arunan Chandravarkar, Marie-Stéphanie Camus, Jérémy Bérard, Karine Murat, Adrian Schmid, Richard Mimna, Hilal A. Lashuel, Manfred Mutter

Journal:

Year:

2007

Language:

english

File:

PDF, 751 KB

english, 2007

17

Structure and function of the molecular chaperone Hsp104 from yeast

Valerie Grimminger-Marquardt, Hilal A. Lashuel

Journal:

Year:

2010

Language:

english

File:

PDF, 982 KB

english, 2010

18

Branched KLVFF Tetramers Strongly Potentiate Inhibition of β-Amyloid Aggregation

Sidhartha M. Chafekar, Hinke Malda, Maarten Merkx, E. W. Meijer, David Viertl, Hilal A. Lashuel, Frank Baas, Wiep Scheper

Journal:

Year:

2007

Language:

english

File:

PDF, 793 KB

english, 2007

19

Switch-Peptides: Design and Characterization of Controllable Super-Amyloid-Forming Host–Guest Peptides as Tools for Identifying Anti-Amyloid Agents

Marie-Stéphanie Camus, Sonia Dos Santos, Arunan Chandravarkar, Bhubaneswar Mandal, Adrian W. Schmid, Gabriele Tuchscherer, Manfred Mutter, Hilal A. Lashuel

Journal:

Year:

2008

Language:

english

File:

PDF, 769 KB

english, 2008

20

Amyloids Go Genomic: Insights Regarding the Sequence Determinants of Prion Formation from Genome-Wide Studies

Hilal A. Lashuel, Rohit V. Pappu

Journal:

Year:

2009

Language:

english

File:

PDF, 598 KB

english, 2009

21

Chemical Synthesis and Expression of the HIV-1 Rev Protein

Peter Siman, Ofrah Blatt, Tal Moyal, Dr. Tsafi Danieli, Dr. Mario Lebendiker, Prof. Hilal A. Lashuel, Prof. Assaf Friedler, Prof. Ashraf Brik

Journal:

Year:

2011

Language:

english

File:

PDF, 462 KB

english, 2011

22

ChemInform Abstract: Amyloidogenic Protein—Membrane Interactions: Mechanistic Insight from Model Systems

Sara M. Butterfield, Hilal A. Lashuel

Journal:

Year:

2010

File:

PDF, 15 KB

2010

23

An integrative in silico methodology for the identification of modulators of macrophage migration inhibitory factor (MIF) tautomerase activity

Farah El Turk, Bruno Fauvet, Hajer Ouertatani-Sakouhi, Adrien Lugari, Stephane Betzi, Philippe Roche, Xavier Morelli, Hilal A. Lashuel

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 2.49 MB

english, 2010

24

Discovery of Inhibitors that Elucidate the Role of UCH-L1 Activity in the H1299 Lung Cancer Cell Line

Yichin Liu, Hilal A. Lashuel, Sungwoon Choi, Xuechao Xing, April Case, Jake Ni, Li-An Yeh, Gregory D. Cuny, Ross L. Stein, Peter T. Lansbury Jr.

Journal:

Chemistry & Biology

Year:

2003

Language:

english

File:

PDF, 720 KB

english, 2003

25

The nucleation of monomeric parallel β-sheet-like structures and their self-assembly in aqueous solution

Penchit Chitnumsub, Wayne R. Fiori, Hilal A. Lashuel, Humberto Diaz, Jeffery W. Kelly

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 798 KB

english, 1999

26

Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model

Preeti J Khandelwal, Sonya B Dumanis, Li Rebekah Feng, Kathleen Maguire-Zeiss, GW Rebeck, Hilal A Lashuel, Charbel EH Moussa

Journal:

Molecular Neurodegeneration

Year:

2010

Language:

english

File:

PDF, 7.54 MB

english, 2010

27

Neurodegenerative disease: Amyloid pores from pathogenic mutations

Lashuel, Hilal A., Hartley, Dean, Petre, Benjamin M., Walz, Thomas, Lansbury, Peter T.

Journal:

Year:

2002

Language:

english

File:

PDF, 63 KB

english, 2002

28

Islam: governments need to reform education and build a scientific culture

Lashuel, Hilal A., Zawia, Nasser

Journal:

Year:

2006

Language:

english

File:

PDF, 91 KB

english, 2006

29

Arab world needs its science diaspora

Lashuel, Hilal A., Al-Delaimy, Wael K.

Journal:

Year:

2011

Language:

english

File:

PDF, 163 KB

english, 2011

30

10.1038/78980

Wemmer, David E., Liu, Kai, Cho, Ho S., Lashuel, Hilal A., Kelly, Jeffery W.

Journal:

Natural Structural Biology

Year:

2000

Language:

english

File:

PDF, 309 KB

english, 2000

31

A century-old debate on protein aggregation and neurodegeneration enters the clinic

Lansbury, Peter T., Lashuel, Hilal A.

Journal:

Year:

2006

Language:

english

File:

PDF, 367 KB

english, 2006

32

Preparation and characterization of toxic Aβ aggregates for structural and functional studies in Alzheimer's disease research

Jan, Asad, Hartley, Dean M, Lashuel, Hilal A

Journal:

Nature Protocols

Year:

2010

Language:

english

File:

PDF, 1.60 MB

english, 2010

33

Interactions among α-synuclein, dopamine, and biomembranes

Jean-Christophe Rochet, Tiago Fleming Outeiro, Kelly A. Conway, Tomas T. Ding, Michael J. Volles, Hilal A. Lashuel, Robert M. Bieganski, Susan L. Lindquist, Peter T. Lansbury

Journal:

Journal of Molecular Neuroscience

Year:

2004

Language:

english

File:

PDF, 184 KB

english, 2004

34

Reactive oxidative species enhance amyloid toxicity in APP/PS1 mouse neurons

Bin Yang, Xiaqin Sun, Hilal Lashuel, Yan Zhang

Journal:

Neuroscience Bulletin

Year:

2012

Language:

english

File:

PDF, 393 KB

english, 2012

35

Protofilaments, Filaments, Ribbons, and Fibrils from Peptidomimetic Self-Assembly: Implications for Amyloid Fibril Formation and Materials Science

Lashuel, Hilal A., LaBrenz, Steven R., Woo, Linda, Serpell, Louise C., Kelly, Jeffery W.

Journal:

Journal of the American Chemical Society

Year:

2000

Language:

english

File:

PDF, 855 KB

english, 2000

36

Recombinant Human Retinol-Binding Protein Refolding, Native Disulfide Formation, and Characterization

Yansheng Xie, Hilal A. Lashuel, Greta J. Miroy, Sergei Dikler, Jeffery W. Kelly

Journal:

Protein Expression and Purification

Year:

1998

Language:

english

File:

PDF, 149 KB

english, 1998

37

Amyloid fibril formation by macrophage migration inhibitory factor

Hilal A. Lashuel, Bayan Aljabari, Einar M. Sigurdsson, Christine N. Metz, Lin Leng, David J.E. Callaway, Richard Bucala

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 423 KB

english, 2005

38

Phosphorylation of α-synuclein is crucial in compensating for proteasomal dysfunction

Hee soon Choi, Hyunjeong Liew, Ahram Jang, Yun-Mi Kim, Hilal Lashuel, Yoo-Hun Suh

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 793 KB

english, 2012

39

Hsp104 Targets Multiple Intermediates on the Amyloid Pathway and Suppresses the Seeding Capacity of Aβ Fibrils and Protofibrils

Muriel Arimon, Valerie Grimminger, Fausto Sanz, Hilal A. Lashuel

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 3.59 MB

english, 2008

40

E46K Parkinson’s-Linked Mutation Enhances C-Terminal-to-N-Terminal Contacts in α-Synuclein

Carla C. Rospigliosi, Sebastian McClendon, Adrian W. Schmid, Trudy F. Ramlall, Patrick Barré, Hilal A. Lashuel, David Eliezer

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 1.97 MB

english, 2009

41

The Anti-Parkinsonian Drug Selegiline Delays the Nucleation Phase of α-Synuclein Aggregation Leading to the Formation of Nontoxic Species

Carolina A. Braga, Cristian Follmer, Fernando L. Palhano, Elias Khattar, Mônica S. Freitas, Luciana Romão, Saviana Di Giovanni, Hilal A. Lashuel, Jerson L. Silva, Debora Foguel

Journal:

Journal of Molecular Biology

Year:

2011

Language:

english

File:

PDF, 2.25 MB

english, 2011

42

Chemical Strategies for Controlling Protein Folding and Elucidating the Molecular Mechanisms of Amyloid Formation and Toxicity

Sara Butterfield, Mirva Hejjaoui, Bruno Fauvet, Loay Awad, Hilal A. Lashuel

Journal:

Journal of Molecular Biology

Year:

2012

Language:

english

File:

PDF, 2.32 MB

english, 2012

43

Production and characterization of astrocyte-derived human apolipoprotein E isoforms from immortalized astrocytes and their interactions with amyloid-β

Masayuki Morikawa, John D. Fryer, Patrick M. Sullivan, Erin A. Christopher, Suzanne E. Wahrle, Ronald B. DeMattos, Mark A. O'Dell, Anne M. Fagan, Hilal A. Lashuel, Thomas Walz, Kiyofumi Asai, David M.

Journal:

Neurobiology of Disease

Year:

2005

Language:

english

File:

PDF, 801 KB

english, 2005

44

Quaternary Structure, Protein Dynamics, and Synaptic Function of SAP97 Controlled by L27 Domain Interactions

Terunaga Nakagawa, Kensuke Futai, Hilal A. Lashuel, Irene Lo, Kenichi Okamoto, Thomas Walz, Yasunori Hayashi, Morgan Sheng

Journal:

Year:

2004

Language:

english

File:

PDF, 852 KB

english, 2004

45

Nuclear import factors importin α and importin β undergo mutually induced conformational changes upon association

Gino Cingolani, Hilal A. Lashuel, Larry Gerace, Christoph W. Müller

Journal:

Year:

2000

Language:

english

File:

PDF, 460 KB

english, 2000

46

Association between the first two immunoglobulin-like domains of the neural cell adhesion molecule N-CAM

Annette R. Atkins, Michael J. Osborne, Hilal A. Lashuel, Gerald M. Edelman, Peter E. Wright, Bruce A. Cunningham, H.Jane Dyson

Journal:

Year:

1999

Language:

english

File:

PDF, 371 KB

english, 1999

47

α-Synuclein, Especially the Parkinson's Disease-associated Mutants, Forms Pore-like Annular and Tubular Protofibrils

Hilal A. Lashuel, Benjamin M. Petre, Joseph Wall, Martha Simon, Richard J. Nowak, Thomas Walz, Peter T. Lansbury Jr

Journal:

Journal of Molecular Biology

Year:

2002

Language:

english

File:

PDF, 2.86 MB

english, 2002

48

Hydration and Packing are Crucial to Amyloidogenesis as Revealed by Pressure Studies on Transthyretin Variants that Either Protect or Worsen Amyloid Disease

Astria D. Ferrão-Gonzales, Leonardo Palmieri, Marcelo Valory, Jerson L. Silva, Hilal Lashuel, Jeffery W. Kelly, Débora Foguel

Journal:

Journal of Molecular Biology

Year:

2003

Language:

english

File:

PDF, 544 KB

english, 2003

49

Mixtures of Wild-type and a Pathogenic (E22G) Form of Aβ40 in Vitro Accumulate Protofibrils, Including Amyloid Pores

Hilal A. Lashuel, Dean M. Hartley, Benjamin M. Petre, Joseph S. Wall, Martha N. Simon, Thomas Walz, Peter T. Lansbury Jr

Journal:

Journal of Molecular Biology

Year:

2003

Language:

english

File:

PDF, 3.75 MB

english, 2003

50

The UCH-L1 Gene Encodes Two Opposing Enzymatic Activities that Affect α-Synuclein Degradation and Parkinson's Disease Susceptibility

Yichin Liu, Lara Fallon, Hilal A. Lashuel, Zhihua Liu, Peter T. Lansbury Jr.

Journal:

Year:

2002

Language:

english

File:

PDF, 453 KB

english, 2002

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